lunes, 6 de agosto de 2012

Cannabis y transtorno bipolar

En Borrador:

http://norml.org/news/2012/08/09/study-cannabis-use-associated-with-superior-cognitive-performance-in-bipolar-patients

Study: Cannabis Use Associated With Superior Cognitive Performance In Bipolar Patients

Thursday, 09 August 2012
Glen Oaks, NY: Bipolar patients with a history of cannabis use demonstrate superior neurocogitive performance compared to patients with no history of use, according to clinical data published online in the journal Psychiatry Research.
Investigators at The Zucker Hillside Hospital in Long Island, NY, along with researchers at the Mount Sinai School of Medicine and the Albert Einstein College of Medicine in New York City compared the performance of 50 bipolar subjects with a history of cannabis use versus 150 bipolar patients with no history of use on a battery of standardized cognitive measures. Patient groups did not differ regarding age, racial background, or highest education level achieved. Bipolar patients with a history of cannabis use had similar age at onset as did patients who did not consume cannabis.
Researchers found that subjects with a history of cannabis use exhibited better neurocognitive performance than that of non-users, but they did not differ significantly on estimates of premorbid IQ.
Authors reported, "Results from our analysis suggest that subjects with bipolar disorder and history of (cannabis use) demonstrate significantly better neurocognitive performance, particularly on measures of attention, processing speed, and working memory. These findings are consistent with a previous study that demonstrated that bipolar subjects with history of cannabis use had superior verbal fluency performance as compared to bipolar patients without a history of cannabis use. Similar results have also been found in schizophrenia in several studies."
They concluded, "These data could be interpreted to suggest that cannabis use may have a beneficial effect on cognitive functioning in patients with severe psychiatric disorders. However, it is also possible that these findings may be due to the requirement for a certain level of cognitive function and related social skills in the acquisition of illicit drugs."
For more information, please contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, "Cognitive and clinical outcomes associated with cannabis use in patients with bipolar I disorder," will appear in Psychiatry Research.

Traducción automática de Google.

Estudio: El cannabis está asociado con un rendimiento superior cognitivo en pacientes bipolares
Jueves, 09 de agosto 2012

Glen Oaks, Nueva York: Los pacientes bipolares con antecedentes de consumo de cannabis demostrar neurocogitive rendimiento superior en comparación con los pacientes sin antecedentes de uso, de acuerdo a los datos clínicos publicados en línea en la revista Investigación Psiquiatría.

Investigadores del Hospital Zucker Hillside en Long Island, Nueva York, junto con investigadores de la Escuela de Medicina Mount Sinai y el Albert Einstein College of Medicine de Nueva York compararon los resultados de 50 pacientes bipolares con antecedentes de consumo de cannabis en comparación con 150 pacientes bipolares sin antecedentes de uso de una batería de medidas estandarizadas cognitivas. Los grupos de pacientes no fueron diferentes en cuanto a edad, raza, o el más alto nivel de educación alcanzado. Los pacientes bipolares con antecedentes de consumo de cannabis tenían la misma edad de inicio al igual que los pacientes que no consumían cannabis.

Los investigadores encontraron que los sujetos con antecedentes de consumo de cannabis mostraron un mejor rendimiento neurocognitivo que la de los no usuarios, pero no hubo diferencias significativas en las estimaciones de CI premórbido.

Autores informó: "Los resultados de nuestro análisis sugieren que los sujetos con trastorno bipolar y la historia de (consumo de cannabis) muestran un rendimiento significativamente mejor neurocognitivo, especialmente en las medidas de atención, velocidad de procesamiento y memoria de trabajo. Estos resultados son consistentes con un estudio previo que demostró que los sujetos bipolares con antecedentes de consumo de cannabis tenían un rendimiento superior fluidez verbal, en comparación con los pacientes bipolares sin antecedentes de consumo de cannabis. Resultados similares han sido encontrados en la esquizofrenia en varios estudios. "

Llegaron a la conclusión, "Estos datos podrían ser interpretado para sugerir que el consumo de cannabis puede tener un efecto beneficioso sobre el funcionamiento cognitivo en pacientes con trastornos psiquiátricos graves. Sin embargo, también es posible que estos hallazgos puede ser debido a la exigencia de un cierto nivel de cognitivo función y relacionados con las habilidades sociales en la adquisición de drogas ilícitas ".

Para obtener más información, póngase en contacto con Paul Armentano, Director Adjunto NORML, en: paul@norml.org. El texto completo del estudio, "los resultados cognitivos y clínicos asociados con el consumo de cannabis en pacientes con trastorno bipolar I," aparecerá en Psychiatry Research.

http://www.medicalnewstoday.com/articles/249006.php
According to a study published online in the journal Psychiatry Research, individuals with bipolar disorder who used cannabis showed higher neurocognitive performance than patients who did not use cannabis.

Researchers at The Zucker Hillside Hospital in Long Island, NY, in collaboration with a team at the Mount Sinai School of Medicine and the Albert Einstein College of Medicine in New York City, examined the difference in cognitive performance among 50 individuals with bipolar disorder who had a history of cannabis use, with 150 bipolar patients who had no history of cannabis use. 

Both groups of patients were similar in age at bipolar onset. In addition, the groups did not differ in racial background, age, or highest education level achieved. 

The team discovered that patients who used cannabis showed superior neurocognitive performance than those who did not. However, patients who used cannabis did not differ considerably on estimates of premorbid IQ. 

The researchers explained:

"Results from our analysis suggest that subjects with bipolar disorder and history of (cannabis use) demonstrate significantly better neurocognitive performance, particularly on measures of attention, processing speed, and working memory.

These findings are consistent with a previous study that demonstrated that bipolar subjects with history of cannabis use had superior verbal fluency performance as compared to bipolar patients without a history of cannabis use. Similar results have also been found in schizophrenia in several studies."


They concluded, "These data could be interpreted to suggest that cannabis use may have a beneficial effect on cognitive functioning in patients with severe psychiatric disorders. However, it is also possible that these findings may be due to the requirement for a certain level of cognitive function and related social skills in the acquisition of illicit drugs."

What is Bipolar Disorder?

Bipolar disorder, more commonly known in the past as manic depression or manic depressive illness, is a mental disorder in which the patient has mood instability. In severe cases the illness can be very disabling.

An individual with bipolar disorder typically has unusual shifts in mood, energy, and the ability to function - these changes can last for weeks and sometimes months.

The fluctuations present in bipolar disorder are nothing like the "ups-and-downs" we all go through - they are much steeper changes and can damage relationships, destroy job prospects, and undermine school performance. Some patients find their symptoms so unbearable that they attempt to commit suicide.

With proper treatment, the majority of patients can lead full and productive lives.

Written by Grace Rattue 
Copyright: Medical News Today 
Not to be reproduced without permission of Medical News Today 

El cannabis mejora la cognición en el trastorno bipolar

Los sujetos con trastorno bipolar que consumen cannabis han demostrado mejor rendimiento en las medidas de atención, velocidad de procesamiento y memoria de trabajo en comparación con los no consumidores de cannabis. En el estudio 50 pacientes con trastorno bipolar y consumidores de cannabis fueron comparados con 150 enfermos no consumidores de cannabis. Según los autores: "Curiosamente, los pacientes bipolares con historia de consumo de cannabis tienen mejor rendimiento neurocognitivo en comparación con los pacientes sin antecedentes de consumo de cannabis".
Hospital Zucker Hillside, Glen Oaks, Nueva York, EE.UU..
Braga RJ, et al. Psychiatry Res. 2012 Jul 17. [en imprenta]



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